IV Imipenem/Cilastatin (Tienam) |
|
| 500mgX4/d | CrCl > 70 mL/min |
| 500mgX3/d | CrCl 41-70 mL/min |
| 250mgX4/d | CrCl 21-40 mL/min |
| 250mgX2/d | CrCl 6-20 mL/min |
| AD and at 12 hour intervals timed from the end of HD | Hemodialysis |
| Not reccomended in CNS infections due to risk of seizures | Pediatric Dose |
| Dose between 60 to 100 mg/kg/day divided every 6 hours; maximum daily dose: 4,000 mg/day | General dose for Infants>3 months, Children, and Adolescents |