IV Amoxicillin / Clavulanate (Augmentin,Clavenir) |
|
| 1g X 3/d | CrCl > 30 mL/min |
| Initial dose: 1 g (once) Maintenance: 0.5g x 2/d | CrCl 10-30 mL/min |
| Initial dose: 1 g (once) Maintenance: 0.5g x 1/d | CrCl < 10 mL/min |
| As for CrCl < 10 Supplemental dose AD: 0.5g | Hemodialysis |
PO Amoxicillin / Clavulanate (Augmentin, Amoxiclav-Teva) |
|
| 875 mg X 2 / d | CrCl > 30 mL/min |
| 250-500 mg X 2 / d | CrCl 10-30 mL/min |
| 250-500 mg X 1 / d | CrCl < 10 mL/min |
| 250-500 mg X1 / d
Supplemental dose of 250-500mg AD on dialysis day |
Hemodialysis |
| Pediatric dosing | |
| IV
25mg amoxicillin/kg/dose q8h (max dose: if ratio is 1:5 then 1 gr per dose every 8 hr; if ratio is 1:10 then 2 gr per dose every 8-12 hr)
|
>3 months,>4kg (less than 3 months or 4 kg same dose q 12 hrs) |
|
PO 45mg amoxicillin/kg/day divided q12h (max. 1.750 gr/day for children above 3m)
90mg amoxicillin/kg/day divided q12h (max. 4gr/day)
|
400mg/5 ml
600mg/5ml
|